If you can get the app. I looked at Waydroid and other apps, but discovered that app I needed was only on the google play store. (I want to see when my kid's bus will arrive - there is no web site, just an app. I suspect it needs google logins or something to use, but I gave up before I figured out how to download the .apk)

No, the architecture still needs to match. If you android app supports x86, you're good. Otherwise, you can technically emulate ARM64 and run it, but the performance will suck ass.