The number of people in the US who die from acetaminophen overdose in a year is anywhere from 500 to 100,000 (!) depending upon which source I use. That's what I got from a quick web search. While it's odd (and suspicious) that there's that wide of a range in the claimed mortality, the fact is that is still a lot more than the number of people who die from drinking too much water, which is so rare that it makes the news whenever it happens.