It's not a fictional disease. They stopped crop rotations as the soil became too fucked up so everyone is using the same GMO corn but because they are identical they are susceptible to the same disease and it can spread rapidly.

This has happened to lots of crops like bananas and is currently happening again.

The beginning of the movie is people trying to just play their baseball game around a sandstorm getting annoyed at scientists for telling them the world is ending to the point where NASA is in hiding.

Not fictional. Likely reality without the, us getting lucky enough to shoot McConaughey through a wormhole bit.

I like the idea of Spec Ops, but the game getting judgemental and preachy about how evil I am when it literally isn't giving me any alternative is a big turn off.

In earlier builds there was actually an option to do the right thing and stop this madness, and it would just roll credits. That was actually brilliant, but too many beta testers kept doing exactly that and wondering if the game was that short, if it was joke, or if they were missing something.... So they removed the option

A shame, because if the game has me on rails, then it's not my fault that terrible shit happens. It's the person who designed the course this way.

It's why I find Undertale to be a better anti-violence message.