I know it's about as subjective a thing as you can get, but I find the ergonomics of the DualSense to be atrocious. Like it's so bad that it hurts my hands to play for too long. I also hate the squishy feel of the triggers when they're not using the gimmicky feedback stuff. Overall, I was pretty amazed at how badly they ruined the controller for the PS5 compared to the PS4 one, IMHO.
It's funny to me to see people say they prefer it but hey... some (read: billions of) people also think Twitter was ever worth using. Different strokes for different folks.