If on Android, NewPipe is a great app. Blocks all ads and let's you create playlists and stuff.

Firefox mobile with Ublock add-on installed is good too.

NewPipe is one of the best recommendations.

There is also LibreTube, and YouTube ReVanced

LibreTube depends on a Piped instance, and YouTube ReVanced will need a specific youtube-version and MicroG for Vanced.

Ignore ReVanced, go for LibreTube. It uses Piped in the backend to access YouTube, and it's got a really nice user interface on Android.

It also automatically blocks ads, skips sponsored segments, supports downloads, PiP, background playing, subscriptions, comments, live videos.

It doesn't rely on shady alternative G services running in the background, doesn't need you to modify any official APKs, it's open source, and you can customize elements you want or do not want to see from YouTube. Give it a go.

EDIT: And here are some bonuses it's got over alternatives: customizable sleep timers, channel groups, subscriptions synced automatically with your desktop browser (via Piped), the ability to proxy and reroute your traffic to YouTube, full Shorts support, live comments for broadcasts.

Revanced. It's an universal dex patcher, primarily targeting Youtube.
it can remove ads and tracking and customize ui.

Newpipe, on F-Droid.

Revanced on mobile phone, Smart tube next on TV.

revanced.app

That is the only official website. Do not install prebuilt apks anywhere else. Use the manager to build them yourself. Ask for help in their subreddit.

Their GitHub.

NewPipe, LibreTube or just Firefox with ublock Origin

Firefox plus ublock origin, then just open youtube.com

If you're willing to sacrifice the perks of using YT with a Google account (commenting, uploading videos, history and playlists saved in cloud, paid content, mostly anything else that might require an account), then I'd recommend NewPipe (especially the fork that incorporates SponsorBlock).

Despite the sacrifices, you don't actually need Play Services in order to use the app, and the playlists/history stuff is made up by storing that locally in your device. It's FOSS under GPL, too!

It also lets you watch other stuff that isn't on YT (Soundcloud, CCC, Bandcamp, PeerTube and most likely others that I forgot), and even lets you download the stuff on them!

I use newpipe from the FOSSdroid repo

To me YouTube vanced with sponsor block, still works pretty fine.

I use LibreTube: https://f-droid.org/en/packages/com.github.libretube/

But I heard that NewPipe is also very good: https://newpipe.net/

I'm looking for a browser on Android which will let me use Ublock Origin and NoScript.

For now I use Brave and a DNS filter on my mobile, it works well for YouTube

For those using/hosting invidious, clipious works pretty well and has sponsorblock integration.

I really like this fork of newpipe. It has sponsorblock and YouTube dislike built in

https://github.com/polymorphicshade/NewPipe

Just use Revanced or Revanced Extanded. If you rooted like me (OnePlus 7 Pro + Crdroid 9.5 + Magisk & LSPosed) just use the magisk module, it work great but on my brother phone (not rooted) he use it with the MicroG without problem but you need to disable the official youtube app if you don't want dupe app

I use Piped (https://github.com/TeamPiped/Piped) for youtube both on desktop and mobile through the browser, though there is also the app LibreTube which uses Piped as backend.