COVID Nimbus Variant Now Leads the U.S. as Cases Grow in 27 States and Emergency Visits Rise
(www.medicaldaily.com)
nimbus 
post
Well, they named in nimbus, of course it's going to be potent!
2025-2026 vaccine vs the new dominant variant, visualized:
The 2025-2026 vaccine was for LP.8.1, which is short for BA.2.86.1.1.11.1.1.1.3.8.1.
But the new dominant variant, NB.1.8.1, is (((BA.2.75.3.1.1.1 + BA.2.10.1.1).1.9.1.13.4.1 + (BA.2.75.3.1.1.1 + BA.2.10.1.1).1.19.1.5.1.1) + BA.2.86.1.1).1.5.1.1.8.1
NB.1.8.1 is short for XDV.1.5.1.1.8.1
XDV is a recombinant variant of XDE and JN.1
XDE is a recombinant variant of FL.13.4.1 and GW.5.1.1
FL.13.4.1 is short for XBB.1.9.1.13.4.1
XBB is a recombinant variant of BM.1.1.1 and BJ.1
BM.1.1.1 is short for BA.2.75.3.1.1.1
BJ.1 is short for BA.2.10.1.1
GW.5.1.1 is short for XBB.1.19.1.5.1.1
XBB is a recombinant variant of BM.1.1.1 and BJ.1
BM.1.1.1 is short for BA.2.75.3.1.1.1
BJ.1 is short for BA.2.10.1.1
JN.1 is short for BA.2.86.1.1
spoiler Abbreviated:
NB.1.8.1
XDV.1.5.1.1.8.1
(XDE + JN.1).1.5.1.1.8.1
((FL.13.4.1 + GW.5.1.1) + BA.2.86.1.1).1.5.1.1.8.1
((XBB.1.9.1.13.4.1 + XBB.1.19.1.5.1.1) + BA.2.86.1.1).1.5.1.1.8.1
(((BA.2.75.3.1.1.1 + BA.2.10.1.1).1.9.1.13.4.1 + (BA.2.75.3.1.1.1 + BA.2.10.1.1).1.19.1.5.1.1) + BA.2.86.1.1).1.5.1.1.8.1
:::
The 2026-2027 vaccine is planned to target XFG (LP.8.1.2 + LF.7, or BA.2.86.1.1.11.1.1.1.3.8.1.2 + BA.2.86.1.1.1.16.1.7). Here is XFG vs Nimbus and the 2025-2026 vaccine target (LP.8.1)
Health authorities are monitoring whether an NB.1.8.1-specific update to the vaccine formulation will be needed for the fall 2026 vaccine cycle
Is that even an option at this point? Prebooking the 2026-2027 vaccine is already open for clinics, and based on past years, it may be available about 5 weeks from now
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