The link is not 100% but two hunters eating from the same deer population and falling ill at around the same time is extremely unlikely to be a coincidence.

We are essentially one mutation away from this spreading between humans and that would be very, very bad.

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[–] 55 points 2 years ago (6 children)

chronic wasting disease is really tragic. that's chronic somebody could have smoked

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  • [–] 22 points 2 years ago (4 children)

    My ashtray with a pile of smushed prerolls all with a half-inch+ of flower

    side-eye-1

    side-eye-2

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  • [–] 32 points 2 years ago

    It's going to be in the soil for a very long time yea

    Hope the prion uptake from eating contaminated plants isn't too frequent

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  • [–] 26 points 2 years ago (1 child)

    Think your link's busted there

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  • [–] 18 points 2 years ago (5 children)

    cwd isn't a virus, it doesn't mutate, it's prions

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  • [–] 17 points 2 years ago (4 children)

    True that it's not a virus but prions can mutate in the sense that they are just proteins like any other, produced according to their genes. The gene coding for the prion protein can mutate, producing a prion that is better at making, e.g., the human analog fold into a prion.

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  • [–] 4 points 2 years ago (1 child)

    They aren't produced according the their genes. They don't affect DNA like viruses do. They are a removed lower energy configuration of a protein. When the removed protein bumps into a healthy form of itself, the forces between the molecules pull the healthy protein into the prion shape. Then they go their separate ways, exponentially eating holes through tissues.

    The protein targeted by CWD is different in cervids, it has like an extra loop that is important for its function. So if a CWD prion bumps into the human version of the protein, nothing happens. But, if some weird interaction allowed it to actually work, it's feasible a human prion could be created.

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  • [–] 1 point 2 years ago*

    Prions are just proteins that can fold in a way that self-propagates by causing other instances of the same (or very similar) protein to also misfold the same way. This is how they cause infectious disease. The downstream impacts vary because it depends on what the misfolded protein actually does in addition to helping other instances misfold. Most often it just accumulates, avoiding destruction by the cell's usual mechanisms of destroying misfolded proteins (most prions that can't avoid this would be destroyed before we could even notice their existence). But even just accumulating a bunch of a prion can be devastating, as their mass can be disruptive and the actual functional amount of the normally folded protein becomes effectively nil.

    But like all proteins, they are indeed still produced according to their genes. Proteins are generated through the transcription and translation processes.

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  • [–] 17 points 2 years ago*

    Prions are the best candidate IMO for a near-to-medium-term human extinction event. If a bad one gets a foothold then median human life expectancy will be like 12 years within a century or two and there'll be nothing to be done about it

    You should probably be scareder of CWD and similar diseases TBQH IMHO PBJ

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  • [–] 16 points 2 years ago* (last edited 2 years ago) (2 children)

    It's everywhere by now, isn't it? When the containment of a new disease is precarious like this, I usually assume the worst has already happened. The people in charge just aren't aware of it yet. If they are, they still don't want to tell the public out of fear of how destabilizing such news could be to the whole system.

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  • [–] [S] 18 points 2 years ago (1 child)

    The maps of affected wild herds only shows a few states, but I've seen deer here in NJ as far back as a decade ago that very much looked like they were sick with CWD. I wouldn't doubt that it's more widespread than we are aware of.

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  • [–] 13 points 2 years ago

    Wow this is just like my post apocalyptic TV show

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  • [–] 12 points 2 years ago (6 children)
  • [–] 23 points 2 years ago (5 children)

    Wait, that deer population has been known to have CWD and they were still like "hey, i guess these are good to eat"? tf is wrong with carnists?

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  • [–] 35 points 2 years ago (2 children)

    I mean this isn't even a carnist thing in as much as this is just a "MUH RIGHT TO PUT MYSELF AND ALL OF HUMANITY AT MASSIVE RISK" thing

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  • [–] 11 points 2 years ago* (4 children)

    If anything this just shows how cowardly hunters are. Who tf shoots a clearly diseased animal and then takes it home acting like they shot it on their own merits?

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  • [–] 8 points 2 years ago (2 children)

    Putting it out of its misery and not wasting what could be good venison meat?

    Sounds more merciful than shooting a young healthy animal.

    But I don't know, I don't hunt.

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  • [–] 3 points 2 years ago (1 child)

    If the poor thing's visibly suffering from CWD, it absolutely is not good meat. When I was living in the sticks, I didn't know a single subsistence hunter who'd eat a visibly-diseased buck-- the sport hunters might've still gone after them, but I don't tolerate sport hunters in my physical locality, so I don't talk to them.

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  • [–] 11 points 2 years ago (8 children)

    Where did this disease even come from?

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  • [–] 25 points 2 years ago (6 children)

    It's a certain protein that got misfolded, if it comes in contact with more of the original protein it causes that to also get misfolded. It can spread kinda similarly to a virus, via bodily fluids, animal-animal contact, in contaminated food/water, and by eating tainted meat in this case. Even if the deer was asymptomatic they can still spread the disease. The way the protein is folded causes it to be resistant to degradation so it can lay dormant for years or maybe decades in the environment. It causes horrifying symptoms causing deer to almost turn into zombies as their bodies waste away.

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  • [–] 11 points 2 years ago (3 children)
  • [–] 14 points 2 years ago (2 children)

    Yeah it's not something to fuck with but we keep forcing factory farmed animals to eat animal by-products/waste, and overcrowd/stress wild animal populations.

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  • [–] 6 points 2 years ago

    I lived in England in the 80s and I’m always terrified that I will find out I have vCJD. It’s believed that symptoms can take decades to show.

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  • [–] 5 points 2 years ago

    How would it spread between humans? Bodily fluids?

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  • [+] 1 point 2 years ago