It really depends on the context. When used as an adjective, it's fine. For example, the sentence "My female coworker has brown hair." is correct. However, when it is used as a noun, it can be dehumanising. For example: "A female at my workplace has brown hair" is dehumanising. It can be used as a noun when talking about non-humans ("After mating, the female will lay her eggs.") or in medicinal context when referring to people with uteruses.
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