I was agreeing with you... In the part that criminalization increases social isolation... It was just a remark towards @Sweetpeaches69, who tries reductio-ad-absurdum, which for weed (like any substance) has negative effects on the body, and mind (and in it's specific case the mixture of the two - brain).

I was mostly trying to tell about the biggest impact of weed I can see (and so I write) is the use during difficult times in life (nobody became an addict out of a fulfilling and good life, fairly sure it is a saying even in English?) can exacerbate life problems.