Theres been quite a few high profile flops in the past decade: supergirl, the flash, the marvels, dark phoenix, joker 2, antman 2, Shazam 2, wonder woman 2, green lantern, Captain America: Brave New World, eternals, justice league, suicide squad 2

Edit: also morbius, madame web, kraven the hunter, thunderbolts, Hellboy reboot, there's probably some im forgetting