Yup, been doing this combo for 5-6 years now.
I use KeePassXC on desktop and KeePassDX on Android. No issues whatsoever.
I do have a NAS so that's my "always on" device for Syncthing. Everything syncs up within like 10-15 seconds when a device connects.
I also use a key file as a pseudo 2FA that I keep on a flash drive, so you'd need my master password and my key file to unlock the database.