submitted 4 months ago* (last edited 4 months ago) by to c/til@lemmy.world
 

"inflammation is now understood to be a key mediator of OA that contributes to cartilage loss and progressive degeneration of affected joints... OA is no longer considered a noninflammatory arthritis or a 'wear and tear' disease"

I heretofore thought age-related cartilage loss was the cause of osteoarthritis and inflammation. Turns out it's the other way around: the inflammation degrades cartilage. Okay, no more slogging through joint pains for me, regardless of how small.

Edit: added a phrase for clarity

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[–] 2 points 4 months ago* (1 child)

i think prednisone's side effect is more apparent if you are on higher doses for longer periods of time, 80-100mg per day. i took it for 2 weeks for severe atopic dermatitis, dint cause any symptoms, since it was a taper too.

for RA, you should request biologic medications, theres a couple out for them already. Likewise with people with psoriasis/psoriatic arthiritis.

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  • [–] 2 points 4 months ago

    I started on biologics after diagnosis and they didn’t work for me. I am on a daily JAK inhibitor and a twice-daily NSAID and that has my pain controlled. The current swelling is something new, and is not painful.

    The long-term prednisone use was to help me manage the pain while seeing if a biologic would work. It helped, but I still had to take ~15 mg of prednisone a day or I was in debilitating pain.

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