Yeah, too much resin caked up can make it nauseating to smoke out of, aside from being disgusting and smelling bad. And eventually it can start clogging if it isn't cleaned.

Get yourself a jar, fill it with everclear (or isopropyl 91%), soak the thing in it for a few hours, then run some water through it. Repeat if necessary, and scrub it with a pipe brush as needed. Probably only needed once every few months or so, depending on how much you use it.

In between deep cleanings, use paper towels or cotton pads with some alcohol to clean the bowl and mouthpiece before or after each session. No big deal.