Don't know if this is particularly relevant as a comparison to your Photoshop idea, but I have successfully run things like windows version of Cascadeur and Blender through Proton; in the case of Blender, it was for running an older Kenshi modding import export plugin, which only supports the Windows version of Blender.
Literally just set it up through Steam, Proton Experimental.
UI scaling / fonts can be a bit wonky, but for just doing the import/export steps, its totally workable, as... a .blend file is a .blend file, so you can do the other edits in a linux version of Blender.
Or, I could probably use ProtonTricks to add some fonts and font subpixel AA dependencies to get it to work 'more right', I remember that being what I ended up doing back when I was still using MO2.
Or, or, you could try Bottles, that would probably be a more sane way to try and set up a more... fully featured, editor type of Windows program, within Linux, it tends to handle those kinds of esoteric dependencies a bit better, has more of them as just part of the default preset.