For one, as far as I know that's a single player game. Anyone with other players around means constant slight readjustments, and having everything you do held back (even if only a tenth of a second- I don't know the actual number, that's a ballpark guesstimate) really adds up.

For almost every game it doesn't matter a whole lot. But when it does, it really matters. Bluetooth headphones pad the audio a smidge too, to the point of rather play without sound instead of late audio. It causes constant sending guessing, and if you're using both your leaky playing in a game state that's already past (although when online you always are anyway but cutting as much out as possible is miles better).