I've worked with 2D CAD programs like Autocad for years, I enjoy working with them. Once I tried 3D modeling, I found the experience frustrating--half of my time was spent typing in parameters anyways. I'm sure with enough practice I could get familiar with it, but modeling 3D shapes with a 2D tool just seems like a losing battle.

There are times when the sculpting ability would be nice, but it doesn't come up that often for me. When I need more complex shapes, I'll use Inkscape to make a 2D profile and import it into OpenSCAD. So far it's been working well for me.