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[–] 3 points 1 year ago*

Johnson & Johnson’s non-mRNA one had some severe side effect incidents that got it pulled, and showed lower vaccine efficacy versus Pfizer and Moderna in trials before then. AstraZeneca’s vaccine was a somewhat similar story.

A lot of vaccines off older tech had no such issues. Notably, Novavax delivered a well tolerated high efficacy shot with more limited post-shot hangovers. Some research indicated that this was particularly true for folks with autoimmune conditions, some cancers, or MECFS.

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