Pretty much every GTA, Duke Nukem, the Witcher series, the God of War series, Yakuza, Unchartered, the Final Fantasy games, the Super Mario games (including Donkey Kong), even Pac-man... and that's just the ones I've played. Then you've got virtually everything featuring Disney characters, Star Wars, as well as most other TV and movie tie-in games (of which there are many).

That's the thing about defaultism, is you can play a straight character and not even remember you've done it because it's just the default. I'll bet you didn't even notice that Pac-man was canonically straight, and yet if Ms. Pac-man was instead called "Pacman's Husband Steve", suddenly Pac-man's one defining trait would be his sexuality.

If nothing else, you've provided an object lesson in just how true OP's meme is.