As far as we know the plastic is mostly not doing anything and is possibly bioinert (thatd be lucky). We don't have anybody to compare it to though, because everybody on earth including the uncontacted tribes has a ton of plastic in em cause microplastics are in every environment including just the rain and every plant and every animal. Would I say it's good to have the equivalent of a plastic spoon in your brain? No, I'd rather not have it there and I'd rather us stop polluting the environment with more microplastics.

I do feel like we lost this struggle, like long term. It's going to be thousands of years before this stuff starts to break down. We can, hopefully, make it not as bad I guess