https://en.wikipedia.org/wiki/Explosive_rat
The CIA overdosed us on LSD in the 50s and 60s, though, so now we're an unpaid think-tank.
A variation of this was demonstrated in the movie The One (at about 2:45 in that video)!
For some reason I thought it was in Fifth Element or Valerian and the City of a Thousand Planets, but it seems I misremembered.