Yes. "Layoff" has a very specific meaning in employment. In the US, it is, in one form or another, ending the employment agreement because there is no longer available work. I.e., "Your position has been eliminated."

That's not the case in the "Everyone has to relocate to (place)" situation. It is not a layoff if you fail to comply. It is the company terminating your employment because you refuse to perform the job they want you to do.