A significant over infusion of nitrogen in high pressure will vaporize (forming bubbles) when pressure is suddenly decreased. Nitrogen intake at relatively the same atmospheric pressure won't cause your blood to boil.
When scuba divers dive fairly deep, the extra pressure from the water above them is often significantly higher than atmosphere, as a result of the pressure and other factors (I'm glossing over a lot of science here), increases nitrogen content in your blood. If the pressure on your body is suddenly decreased to atmospheric pressure, then nitrogen bubbles form and it can be fatal. Most commonly it just gives you, what is referred to as, "the bends"
Simply being exposed to a high nitrogen atmosphere, without the added pressure and conditions found in scuba, your blood will not form bubbles, nor boil.
I haven't done any examination of biological reactions to other, less common gases. Noble gases, as far as I'm aware, don't often appear naturally, and it's uncommon for such an environment to exist accidentally. Unless someone is storing large quantities of Noble gases in a poorly ventilated, enclosed space, while the containment vessel is leaking, I don't think it would be possible to have such a scenario occur.
Due to this, I have never felt the need to look into it. It just seems so unlikely that anyone would find themselves in that situation, and if such a situation was likely due to workplace related hazards, special training would be provided. Got the general population, unless they happened to be in a valley where a tanker truck was transporting a heavier-than-air Noble gas, on a particularly still day, the probability of exposure is astronomical.
However, CO2 poisoning can happen in your own home. Along with CO poisoning, and more. You can literally suffocate in your own home. While fairly unlikely, it's significantly more probable than pretty much anything else we've discussed. Nitrogen bubbles in the blood is only a risk for those exposed to high pressure areas, such as scuba divers, so I'd give that a second most likely, out of what we have discussed, and it's basically impossible to end up with nitrogen hypoxia without being in very specific conditions, so that would be near the bottom of my list of what's likely.
That being said, personally, I have plenty of CO and CO2 detectors around my living areas, and anytime there's a rise in concentration of anything that could be harmful, I tend to take action. I also have a radon meter in my basement, which I also keep an eye on.
I already know that my home needs better ventilation to outside, and I'm considering my options for an ERV. I also need something to mitigate radon, which is an entirely other matter. Radon issues are more systemic, and less acute, so it's a bit far down on the priority list for now. I have more urgent matters. My radon levels are not great, but not critical.
I'm a data nerd, and I've been tracking my living space's atmospheric metrics for years.