Lwaxana: Victory by (threat of) snu-snu.

Hoshi, any day. Linguistic genius. Figured out new languages without any data. For fun.

C3PO might not be as adept, as his programming might be limited. His function was a translator but did he have the capability to learn new languages?

Lwaxana is not a translator. She's a diplomat. She may be able to detect that all the alien men in the known universe want her but she can't translate their language for anyone.

If anyone from TNG was a superior translator, it was probably data. He was designed to learn and grow.

A new challenger approaches!

My money's on the heir to the Holy Rings of Betazed.

A Betazoid doesn't even need you to speak. Remember she caught those handsome assassins.

Win at what?

Lwaxana wins by far, she can sense the hidden intentions behind the words.