On Twitch they managed to outplay even uBlock, because the streaming is realtime and if you skip the ad segments, there’s no data to fall back to and the backend won’t send you the regular segments until the ad break is over (from what I understand). So at best you get a waiting screen instead of an ad.

Yes, you get a "commercial break in progress" banner, but it's not loading ads when watching through HLS.

Ads on Twitch are not nearly as bad as on YouTube tho, so I actually have an exception for Twitch ads. I usually only watch esports tournaments and they make sure there are no ad breaks during games, just between segments. And on the rare occasion that I watch a regular stream, I get an ad or two maybe once every 45 minutes, which is fair.