Watching this is definitely not one of my proudest life phases. I remember it really got to me with neurodivergence and how they chose to depict that. Also it's incredibly violent to fat people, the way Cartman gets portayed and what the supposed reasons are for his behaviour.
Someone posted a Red Sails article here yesterday that goes over the way entertainment conditions us to the status quo. I think South Park is a perfect example of that, in making horrible be supposedly mainstream.