So I've been doing subcutaneous E injections for close to 11 months at this point¹, and my most recent one turned out kinda weird. It hurt a bit more than usual going in, there was a lot less resistance when pushing the plunger in (got everything injected in less time than normal), and there was significantly more blood than I'm used to after removing the needle (typically there's only a tiny speck if anything, this time nearly the entire cotton part of the band-aid is stained red). It's been about 2 days now and there's a ~1cm diameter bruise at the injection spot, which is also something I haven't seen before.

The only thing I can think of is that I must've gotten unlucky and managed to hit a blood vessel. If that is the case though, my understanding of how injections work tells me that this will dramatically affect the release curve - rather than being deposited into fat tissue and slowly being released into the bloodstream, I assume this would mean much of the EEn was dumped directly into the blood where it would then be converted into E2 and consumed/destroyed within hours or a few days at most. Am I overthinking this? Should I do another shot to make sure my levels don't crash down in case my hypothesis is correct, or should I just stick to my usual weekly schedule?

¹ probably not relevant, but including this anyway: I'm injecting 0.13 mL of EEn (40 mg/mL, in MCT oil) once per week using 30G, 1/2in long needles

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[–] 2 points 21 hours ago*

thank you!! we would not call it thorough by any means, but then again anything evidence-based goes a long way compared to pure conjecture, i.e. so much of the internet. we just wanna make the world a better place.

on a more personal level we'd say we absolutely disparage fearmongering and saying scary stuff to get someone/many to do stuff, even if it is good stuff. the stress and fear associated with a blown-out concern can in the end be harder to deal with than the concern itself, and leads to real difficulties for all involved! hell, being frequently stressed for extended periods of time is a proven health risk. stress has its valid places but we shouldn't try and cause undue amounts of it.

please do be curious though, we like super admire that. best wishes <3

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