EDIT: For some context, I recently gave podman another go. I have a few services on my homelab server set up in docker containers, so I tried migrating to podman.
After the second major bug (open issue on github) I encountered looked like it would require completely dropping using compose files to work around, I gave up and went back to docker.
I like the idea of podman, but it’s just not stable. I’ll try again in a year or so.
As a bonus, docker’s CLI is significantly nicer.
It does have a larger file size compared to compose, sure. The big advantage of quadlets is that systemd will handle things in the event of a failure. It makes it a great option for production environments where you will not need to update your config files as much. It also allows you to have more control over when each application starts, if they rely on a specific disk mount or service running on the system. I'm sure someone else can provide more benefits who use them in a production environment.