Those isos from scene releases have a higher chance of working. Their setup wizards are simpler and should work under wine. I have used updates from RUNE and such and they worked fine. Fitgirl's installer doesn't work probably because of the decompression it does.
The important thing is to install the games on ext4 or btrfs because the read performance from NTFS is kinda bad. So while NTFS will work for audio-video, games don't work well on it.
