I haven't tried the webcam, but everything else, including WiFi, worked out of the box for me. The KDE version uses modern Plasma and is not a distro that moves hell and high water to get something working on a potato, but overall it is designed with middle-old machines like these in mind.
I'm sure a million other distros will work as well or better, but I do like MX, and it made me smile to see a child of the Mepis LiveCDs I used 20 years ago is still around.