The Uplift Series is a gem. Copied directly from Wiki because it's succinct yet thorough:
The Five Galaxies are filled with alien races, all of whom were "uplifted" into sentience by another race through the use of directed breeding. As "payment" for being made sentient, the uplifted races are subservient to their uplifters for a period of time. All existing races have reached sentience through this process, and follow a common evolution in which the races become free of their uplifters, enter a period of independent power, and then fade and eventually disappear.
The arrival of a human ship at a populated star upsets the established races as humanity reached sentience on their own. This had been believed to be impossible, nothing of the sort is known in the eons-old galactic library. This leads to great arguments among the alien powers. Humanity begins to uplift other species on Earth, including chimpanzees and dolphins, but does not demand subservience.