Personally, I've adjusted dozens of sampler values, written middlewares, llama-server scripts and configuration loading mechanisms, openai api compatible HTTP proxies, and even a python3 API for accessing context information and being able to switch models on the fly. I've even created a local model benchmark performance script.
But besides running some scripts which others have made to tune a model specifically with specific input parameters, not really. Honestly, I have a lot to learn.