If I may, I'd rather prefer a translation layer like Wine, but for Android. Thankfully, it's in the works. Soon™.

I do expect that Waydroid's stocks will increase tremendously as Valve's Lepton is based on it.

As for your query, it depends mostly on your sensibilities:

• Waydroid is lighter and is ever so slightly better integrated.
• VB offers superior sandboxing (and thus improved security).

FWIW, I've had better experiences with Waydroid, but your mileage may vary.