I've been using Graphene for years at this point, and so far it has been amazing.

I have two profiles, main one without Google Play services, and fortunately a lot of apps just work out even without them. Some complain about it, but still work at least as far core functionality I want is considered, and for the few that don't, I have a second profile that runs sandboxed Play Services and just switch when needed.

I'm a little bit worried about Google's push around installing apps from other sources than orignal Play Store, or the new integrity API, but I'm willing to just stop using any app that requires it, and change banks to one that either doesn't require an app for login, or can work without play services. Fortunately, my current one works without, for now (mBank).