Not sure if you're really asking or if its rhetorical, so forgive me if I'm way off, but in doubt it is a reference to how rpg players (of the tabletop kind) will (try to) do inane shit at some point in any given game, such as fucking a dragon. Hence the great overlap between the respective skillets of managers and dungeon masters. And I assume parents of toddlers.

You put ANYTHING in a DnD and you better be prepared for your players to fight it or fuck it and usually both