Yes, and from what I understood:
- Steam is still 32bit. Two-thirds of Bazzite's user base use the OS on handhelds requiring Steam's gaming mode front-end. Installing Steam as a flatpak removes the ability to boot into gaming mode, and so alienating two-thirds of Bazzite's user base.
- It will kill support for older games that are still 32bit. Wine's WoW64 isn't ready yet, and even so, building custom Proton for 32bit support (e.g. Including all the 32bit libraries inside of Proton itself) on top of the Proton provided by Valve is going to be very messy.
- OBS requires 32bit packages to capture video data from 32bit games. If 32bit is no longer supported, this'll kill streamers playing older games (OBS is probably the most widely used software by streamers and game recorders).
- It would kill VR on Bazzite, as VR still makes use of 32bit features (I'm not sure why or which ones, but that's what's said).