Almost no one does one thing to the exclusion of all else, so few, if any, people are getting their knowledge purely from memes, but it doesn't have to be exclusive to have an effect. Someone who drinks a gallon of soda a day isn't necessarily getting all of their nutritional intake from soda, and, to borrow the phrase, god help them if so, but it is going to have effects on their life. Treating politics as entertainment also has secondary effects. Just like drinking soda can train your tongue to expect that level of sweetness, which can lead to troubling dietary choices, political humor trains you expect a punchline in a discussion about policy, which can lead to bad political choices.

And notice there how you changed what I said to argue against a point I didn't make. I talked about jokes as a substitute for sex ed. You talked about jokes after sex ed. There is no mandated political ed class after which to make jokes. The shallow coverage on things like Oliver, tiktok, or other comedy shows is often the deepest, or the only, examination of a political subject people actually ingest, maybe supplemented by a few headlines, a shallow newscast, and an article they didn't finish. They aren't making memes about the thing they learned during an in-depth intended-to-inform class. They are making memes based on the memes they laughed at because of the vague half-knowledge they got from the media atmosphere.

Jokes have their place. No one would argue for a life completely lacking in humor, but, just like your example of rape, a subject that is extremely serious because of the long lasting and possibly life-destroying effect it can have on people, politics is too serious to be joked about in the public sphere. Joking about it fails to take serious something that can leave someone alive, but utterly unable to live.