Bret Weinstein is kind of a moron. I've been saying this for years.
Edit: I listened to Bret, even though I still think he's a moron the article completely misrepresents what he said. The article:
The specific idea that AIDS is spread through poppers—a party drug with a long medical and recreational history—first circulated as HIV began to spread in the 1980s.
My understanding from the snippet is that party drugs trigger AIDS, not spread it. Honestly this is a perfectly reasonable take, loading your body with drugs, poor sleep, poor diet can easily lead to a compromised immune system. I'm guessing the hypothesis is that HIV runs rampant in this state and destroys the immune system leading to AIDS more easily than if you weren't taking drugs. Not pushing your body, specially when you already have HIV, is generally a good idea.