For some added context, this is a picture of Mr Popo and I believe the line is specifically from DBZA.
A special group of youtubers redid the entire manga series up to a point with voice actors and it's funny as fuck. For example, Mr. Popo is now a chtuluesk entity that is way stronger than anyone and doesn't give a fuck about anyone's safety. Try "Mr popo abridged" and enjoy