The N-word was reclaimed by black people to be used with those connotations by taking the original word and its meanings and subverting them into something either positive or neutral. The exact same thing happened with the word queer.
It's a very conscious act to reclaim terms like that.
I'm not saying that the R-slur is beyond reclamation, far from it, but it's not going to be reclaimed by people who aren't the object of the term and it's not going to be reclaimed by using the word in exactly the same way that it has historically been used.
Honestly Keffals' proclaiming her autistic status is just a veneer of progressivism to make her audience feel comfortable with her use of slurs.