no but the dev controls it. if the dev is using the ndk and the dev is not doing the extra step of disabling/configuring it there should be in "fat" apk with each binary for each platform according to the docs. then the installer can figure out which version to use.

the x86(/_64) version is used for Chromebooks i believe. some devs will split the apk if they configured it to reduce size so you would need to specifically go get an x86 apk version.

the cases where a dev would disable it is if they only want to support specific instructions that might be platform specific or say a library they use doesn't support target ABIs