I didn't even have to balance the tire. I only broke the bead on one side, and pushed the tire sidewall back enough to get my hand in there and pull the sensors out. They are very lightweight and didn't throw the balance off that I could notice.
I do have a persistent TPMS warning light, but some work with a screwdriver had the bulb out. My truck was different, it has a warning light and a warning message on the cluster LCD screen, but with Forscan I was able to just disable the TPMS function.