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Lastest Riot Vanguard Update Can Brick Your Hardware (If You're a Cheater)
(insider-gaming.com)
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It doesn't brick any hardware at all.
They're using the IOMMU page table enforcement hardware (VT-d/AMD-Vi) to block DMA access to specific areas of memory.
This press coverage is largely just Valorant tooting their own horn. It will block the current generation of DMA hardware but there are several ways to bypass the IOMMU enforcement via hardware.
So, they simply rendered the current generation of DMA hardware obsolete. There will be new DMA cheats pretending to be Thunderbolt 4 controller devices (which are trusted to do their own IOMMU enforcement) or a PCI-e ATS device.