The pathway out of the US is increasingly looking like a pathway into the Global South.

Except we're in the transitional period between American and Chinese hegemonies, so there's not much demand for Western scientists just yet. Places looking to radically improve their standing in the new world order don't quite have the demand for foreign scientists that the West does/used to have just yet. While cream of the crop researchers will be able to do pretty well for themselves, I think we're about a generation away from a time when a "normal" above average Western scientist or engineer will be able to move to the (at this point former) Global South without taking a large hit to their quality of life.