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po-tay-toes
(thelemmy.club)
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this post was submitted on 28 Mar 2026
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I'd agree if you weren't misquoting me and referring to another statement out of context.
Do you have any specific criticism based on both what I actually wrote and actual medical science?
Edit: I expect it's how I mentioned tricyclics as a first-line treatment. Within anti depressants, SSRIs/SNRIs > tricyclic > MAOI due to side effect profiles, but all will often (but not always) be trialed before moving to benzodiazepine monotherapy or higher dose/frequency adjuvant therapy.
Some studies suggest TCAs are more effective than SSRIs. MAOIs are absolutely more effective than both, but their side effect profiles and restrictions due to dietary/medication interactions can be brutal.
The greatest evidence for this cognitive damage is a self-selected Internet survey: https://pmc.ncbi.nlm.nih.gov/articles/PMC10309976/
We call that "pretty low quality" data in science and public health. Unsatisfied customers are more likely to write a review. lI'm not saying it's not possible, but actual data is scant.