exFAT is great for compatibility but it doesn't have journaling, so if there's a power outage while writing to a file, you can expect the file to get corrupted and unusable (which sucks). apart from that, yeah, it's great.

what i can recommend if you're working in a big organization or group or sth is to use a network drive, i.e. a drive that's accessed over the network. you typically don't have problems there.