I can't speak to the Quest support as I don't have one, but my Index definitely had issues when I first switched to Linux fulltime. I had been dual-booting for about a year prior to that. But over the last year, it's gotten better and most titles I've tried lately seem to just work the same way they did on Windows.

I do still have this persistent issue where my computer treats the headset as the primary display during bootup if have it plugged in, but that's OS independent and starts at POST.

I've also seen some changelogs a while back suggesting Valve was trying to get OpenVR and SteamVR more compatible and make them both work better on Linux. I don't know what issues you were having or how recently but it might be worth digging into again if it's something you care about.