I'm personally using Firefox multi-account containers. It's way better than switching to profiles.
I have for example one container type for work and for specific URL i even made it so they are always opened in this containers. It's really useful as cookies are separated.
I'm coupling it with Simple Tab Groups where I can group tabs together based on criterias (For example all tabs running in my "work" container). At the beginning of my work day I switch to my "work" group and all my tabs on my window are work related and at the end I switch back to my "personal" group with my usual tabs.
It's a bit more work but lets me be completely chromium free :)