Yes. It does I2C. It’s also a pi Pico core so dual core. So you could use a separate core to drive the screen independently from the keyboard to keep them fast.
Edit: actually the i2C is not exposed on the pins, but you should be able to use the BitBang_I2C library to expose them on any pair of GPIO pins. I’ll try it out and report back.
Edit2: actually, no need for that library you can set virtual I2C to any pins I tried it with another project on the same board.