Riot Games talk Vanguard anti-cheat for League of Legends and why it's a no for Linux
(www.gamingonlinux.com)
League just doesn't have that many 'traditional' cheaters and the game lends itself to server-side AC way more than most. The cheaters in League are more often win-traders at high elos and smurfs in low elos. Also lots of feeding and trolling. So I have no idea why they are adding Vanguard, a good reason to stop playing the game though.