this post was submitted on 11 Jul 2024
905 points (98.7% liked)

memes

10203 readers
2328 users here now

Community rules

1. Be civilNo trolling, bigotry or other insulting / annoying behaviour

2. No politicsThis is non-politics community. For political memes please go to [email protected]

3. No recent repostsCheck for reposts when posting a meme, you can only repost after 1 month

4. No botsNo bots without the express approval of the mods or the admins

5. No Spam/AdsNo advertisements or spam. This is an instance rule and the only way to live.

Sister communities

founded 1 year ago
MODERATORS
[email protected]
[email protected]
[email protected]
905
Chronic pain mood (lemmy.world)
submitted 4 months ago by [email protected] to c/[email protected]
73 comments fedilink hide all child comments
 
you are viewing a single comment's thread
view the rest of the comments
[โ€“] [email protected] 5 points 3 months ago (1 children)

Some of the anti-depressant meds affect things like GABA or norepinephrine (so an SNRI as opposed to SSRI), so it's not just the anti-depressant angle, as they're often used in much smaller doses than when used for depression.

It's pretty fascinating stuff - I just learned about the norepinephrine angle recently. The thinking is that chronic pain causes people to become more sensitive to small pain signals - their nervous system is over-sensitized to pain, and these meds help with reducing the signaling/response to signals.

If you're curious, lookup gabapentin (it's been around for at least 30 years) or tramadol (an SNRI), which has also been around a long time.

[โ€“] [email protected] 1 points 3 months ago

My wife has been on both of those. Neither at the moment.